aceK protein (Pseudomonas putida KT2440) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (571 aa)
		(Pseudomonas putida KT2440)
Predicted Functional Partners:
	thiE	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophos [...] (207 aa)	•	0.899
	ribE-2	Riboflavin synthase, alpha subunit (209 aa)	•	0.899
	wecB	UDP-N-acetylglucosamine 2-epimerase (380 aa)	•	0.899
	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (351 aa)	•	0.899
	PP1348	MutT/nudix family protein/thiamine-phosphate pyrophosphorylase, putative (314 aa)	•	0.899
	adh	2,3-butanediol dehydrogenase (362 aa)	•	0.899
	thiL	Thiamine monophosphate kinase (322 aa)	•	0.899
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (158 aa)	•	0.899
	ribE-1	Riboflavin synthase, alpha subunit (221 aa)	•	0.899
	ribD	Riboflavin biosynthesis protein RibD (378 aa)	•	0.899

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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