Ikbkb protein (Mus musculus) - STRING interaction network

Ikbkb protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Ikbkb	inhibitor of kappaB kinase beta; Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF- kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3 (By similarity) (757 aa)
		(Mus musculus)
Predicted Functional Partners:
	Ikbkg	inhibitor of kappaB kinase gamma; Regulatory subunit of the IKK core complex which phosphorylat [...] (430 aa)	•	•	•	0.999
	Nfkbia	nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; Inhibits the act [...] (314 aa)	•	•	•	0.999
	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian); NF-kappa-B is a pleiotropic trans [...] (549 aa)	•	•	•	0.999
	Bcl10	B-cell leukemia/lymphoma 10; Promotes apoptosis, pro-caspase-9 maturation and activation of NF- [...] (277 aa)	•	•	•	0.998
	Nfkb1	nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; NF-kappa-B is a pleiotrop [...] (971 aa)	•	•	•	0.997
	Nfkbib	nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; Inhibits NF-kappa [...] (359 aa)	•	•	•	0.997
	Rel	reticuloendotheliosis oncogene; Proto-oncogene that may play a role in differentiation and lymp [...] (588 aa)		•	•	0.995
	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B; NF-kappa-B is a pleiotropic trans [...] (558 aa)		•	•	0.995
	Tnf	tumor necrosis factor; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly s [...] (235 aa)		•	•	0.992
	Card11	caspase recruitment domain family, member 11; Activates NF-kappa-B via BCL10 and IKK. Stimulate [...] (1159 aa)		•	•	0.992

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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