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  Socs4 protein (Mus musculus) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Socs4
suppressor of cytokine signaling 4; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) (436 aa)
(Mus musculus)
Predicted Functional Partners:
Ghr
growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating pos [...] (650 aa)
     •• 0.805
Socs3
suppressor of cytokine signaling 3; SOCS family proteins form part of a classical negative feed [...] (225 aa)
     •••0.803
Il2rg
interleukin 2 receptor, gamma chain; Common subunit for the receptors for a variety of interleu [...] (369 aa)
     •  0.803
Socs1
suppressor of cytokine signaling 1; SOCS family proteins form part of a classical negative feed [...] (212 aa)
     •••0.803
Il4r
interleukin 4 receptor, alpha; Receptor for both interleukin 4 and interleukin 13. Couples to t [...] (810 aa)
     •  0.802
Socs2
suppressor of cytokine signaling 2; SOCS family proteins form part of a classical negative feed [...] (198 aa)
     •••0.801
Il6st
interleukin 6 signal transducer; Signal-transducing molecule. The receptor systems for IL6, LIF [...] (917 aa)
     •• 0.800
Socs5
suppressor of cytokine signaling 5; SOCS family proteins form part of a classical negative feed [...] (536 aa)
     •••0.800
Il3ra
interleukin 3 receptor, alpha chain; In mouse, there are two classes of high-affinity IL3 recep [...] (396 aa)
     •  0.800
Il11ra1
interleukin 11 receptor, alpha chain 1; Receptor for interleukin-11. The receptor systems for I [...] (432 aa)
     •  0.800
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth
       
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