node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ap4e1 | Fam214a | ENSMUSP00000002063 | ENSMUSP00000080442 | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | Protein FAM214A. | 0.437 |
Ap4e1 | Hmg20b | ENSMUSP00000002063 | ENSMUSP00000020454 | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | High mobility group 20B; Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity). | 0.419 |
Ap4e1 | Lmbrd2 | ENSMUSP00000002063 | ENSMUSP00000154020 | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1. | 0.600 |
Ap4e1 | Mex3d | ENSMUSP00000002063 | ENSMUSP00000100987 | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | RNA-binding protein MEX3D; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms. | 0.419 |
Ap4e1 | Pigo | ENSMUSP00000002063 | ENSMUSP00000095713 | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI- anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. | 0.469 |
Btbd2 | Fam214a | ENSMUSP00000003434 | ENSMUSP00000080442 | BTB (POZ) domain-containing 2. | Protein FAM214A. | 0.487 |
Btbd2 | Lmbrd2 | ENSMUSP00000003434 | ENSMUSP00000154020 | BTB (POZ) domain-containing 2. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1. | 0.542 |
Btbd2 | Mex3d | ENSMUSP00000003434 | ENSMUSP00000100987 | BTB (POZ) domain-containing 2. | RNA-binding protein MEX3D; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms. | 0.442 |
Btbd2 | Pigo | ENSMUSP00000003434 | ENSMUSP00000095713 | BTB (POZ) domain-containing 2. | GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI- anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. | 0.436 |
Btbd2 | Rsl24d1 | ENSMUSP00000003434 | ENSMUSP00000034738 | BTB (POZ) domain-containing 2. | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). | 0.450 |
Capsl | Depdc1b | ENSMUSP00000035663 | ENSMUSP00000059291 | Calcyphosin-like protein. | DEP domain-containing protein 1B. | 0.511 |
Capsl | Lmbrd2 | ENSMUSP00000035663 | ENSMUSP00000154020 | Calcyphosin-like protein. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1. | 0.778 |
Depdc1b | Capsl | ENSMUSP00000059291 | ENSMUSP00000035663 | DEP domain-containing protein 1B. | Calcyphosin-like protein. | 0.511 |
Depdc1b | Lmbrd2 | ENSMUSP00000059291 | ENSMUSP00000154020 | DEP domain-containing protein 1B. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1. | 0.582 |
Fam214a | Ap4e1 | ENSMUSP00000080442 | ENSMUSP00000002063 | Protein FAM214A. | AP-4 complex subunit epsilon-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper [...] | 0.437 |
Fam214a | Btbd2 | ENSMUSP00000080442 | ENSMUSP00000003434 | Protein FAM214A. | BTB (POZ) domain-containing 2. | 0.487 |
Fam214a | Hmg20b | ENSMUSP00000080442 | ENSMUSP00000020454 | Protein FAM214A. | High mobility group 20B; Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity). | 0.463 |
Fam214a | Lmbrd2 | ENSMUSP00000080442 | ENSMUSP00000154020 | Protein FAM214A. | G-protein coupled receptor-associated protein LMBRD2; Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway. May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1. | 0.628 |
Fam214a | Mex3d | ENSMUSP00000080442 | ENSMUSP00000100987 | Protein FAM214A. | RNA-binding protein MEX3D; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms. | 0.482 |
Fam214a | Pigo | ENSMUSP00000080442 | ENSMUSP00000095713 | Protein FAM214A. | GPI ethanolamine phosphate transferase 3; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI- anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. | 0.503 |