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  Cacna1a protein (Mus musculus) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin- IVA (omega-Aga-IVA). [...] (2369 aa)
(Mus musculus)
Predicted Functional Partners:
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit; The beta subunit of voltage-dependent calci [...] (519 aa)
     0.982
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit; The beta subunit of voltage-dependent calci [...] (597 aa)
     0.955
Cacng2
calcium channel, voltage-dependent, gamma subunit 2; Thought to stabilize the calcium channel i [...] (323 aa)
      0.955
Bhlhb4
basic helix-loop-helix domain containing, class B4; May function as transcriptional repressor. [...] (223 aa)
       0.952
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit; The beta subunit of voltage-dependent calci [...] (484 aa)
      0.949
Cacnb2
calcium channel, voltage-dependent, beta 2 subunit; The beta subunit of voltage-dependent calci [...] (655 aa)
      0.946
Atxn3
ataxin 3; Interacts with key regulators of transcription and represses transcription. Acts as a [...] (355 aa)
       0.938
Cacna2d2
calcium channel, voltage-dependent, alpha 2/delta subunit 2 (1154 aa)
      0.937
Atxn7
ataxin 7; Involved in neurodegeneration. Acts as component of the STAGA transcription coactivat [...] (867 aa)
       0.929
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit; Voltage-sensitive calcium channel [...] (2122 aa)
     0.917
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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