Sfrp4 protein (Mus musculus) - STRING interaction network

Sfrp4 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Sfrp4	secreted frizzled-related protein 4; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity) (351 aa)
		(Mus musculus)
Predicted Functional Partners:
	Wnt3a	wingless-related MMTV integration site 3A; Ligand for members of the frizzled family of seven t [...] (352 aa)	•	•		0.987
	Wnt6	wingless-related MMTV integration site 6; Ligand for members of the frizzled family of seven tr [...] (364 aa)	•	•		0.928
	Wnt9a	wingless-type MMTV integration site 9A; Ligand for members of the frizzled family of seven tran [...] (365 aa)	•	•		0.889
	Wnt11	wingless-related MMTV integration site 11; Ligand for members of the frizzled family of seven t [...] (354 aa)	•	•		0.878
	Wnt10b	wingless related MMTV integration site 10b; Ligand for members of the frizzled family of seven [...] (389 aa)	•	•		0.872
	Wnt2	wingless-related MMTV integration site 2; Ligand for members of the frizzled family of seven tr [...] (360 aa)	•	•		0.864
	Wnt5a	wingless-related MMTV integration site 5A; Ligand for members of the frizzled family of seven t [...] (380 aa)	•	•		0.856
	Sfrp2	secreted frizzled-related protein 2; Soluble frizzled-related proteins (sFRPS) function as modu [...] (295 aa)	•	•	•	0.852
	Sfrp1	secreted frizzled-related protein 1; Soluble frizzled-related proteins (sFRPS) function as modu [...] (314 aa)	•	•	•	0.848
	Sfrp5	secreted frizzled-related sequence protein 5; Soluble frizzled-related proteins (sFRPS) functio [...] (314 aa)	•	•	•	0.842

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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