PLCB1 protein (Homo sapiens) - STRING interaction network

PLCB1 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PLCB1	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154); The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (1216 aa)
		(Homo sapiens)
Predicted Functional Partners:
	GNAQ	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha [...] (359 aa)	•	•	•		0.996
	PRKCA	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A); This is a calcium-activated, ph [...] (672 aa)	•	•	•		0.964
	PRKCD	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta); This is calcium-independent, phospholi [...] (676 aa)	•	•	•		0.963
	GRM1	Metabotropic glutamate receptor 1 precursor (mGluR1) (1194 aa)		•	•		0.951
	DGKA	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase a [...] (735 aa)		•	•		0.945
	DGKZ	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta [...] (1117 aa)		•	•		0.944
	CAMK2A	Calcium/calmodulin-dependent protein kinase type II alpha chain (EC 2.7.11.17) (CaM-kinase II a [...] (489 aa)		•	•		0.929
	EDN1	Endothelin-1 precursor (Preproendothelin-1) (PPET1) [Contains- Endothelin-1 (ET-1); Big endothe [...] (212 aa)		•	•		0.929
	PLCG1	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositi [...] (1412 aa)		•	•	•	0.928
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (P [...] (1070 aa)		•	•		0.923

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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