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  PLCB3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PLCB3
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3); The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (1234 aa)
(Homo sapiens)
Predicted Functional Partners:
SLC9A3R2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) [...] (337 aa)
    ••• 0.991
GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha [...] (359 aa)
     •• 0.977
CAMK2G
Calcium/calmodulin-dependent protein kinase type II gamma chain (EC 2.7.11.17) (CaM-kinase II g [...] (556 aa)
    ••• 0.942
CAMK2B
Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II be [...] (666 aa)
    ••• 0.939
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (T [...] (2758 aa)
     •• 0.934
EDN1
Endothelin-1 precursor (Preproendothelin-1) (PPET1) [Contains- Endothelin-1 (ET-1); Big endothe [...] (212 aa)
     •• 0.929
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (P [...] (1070 aa)
     •• 0.923
PLCG1
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositi [...] (1412 aa)
     •••0.921
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-ph [...] (668 aa)
     •• 0.919
PLCD1
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositi [...] (777 aa)
     •••0.917
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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