STRING 9.1 
  DOCK8 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DOCK8
dedicator of cytokinesis 8; Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP (By similarity) (2031 aa)
(Homo sapiens)
Predicted Functional Partners:
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
     0.969
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
     0.968
DOCK1
dedicator of cytokinesis 1; Involved in cytoskeletal rearrangements required for phagocytosis o [...] (1931 aa)
     0.924
DOCK11
dedicator of cytokinesis 11; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by e [...] (2073 aa)
    0.910
DOCK9
dedicator of cytokinesis 9; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by ex [...] (2068 aa)
     0.904
DOCK6
dedicator of cytokinesis 6; Potential guanine nucleotide exchange factor (GEF). GEF proteins ac [...] (2047 aa)
     0.902
RHOJ
ras homolog gene family, member J; GTP-binding protein with GTPase activity. Elicits the format [...] (214 aa)
      0.888
KANK1
KN motif and ankyrin repeat domains 1; Potential tumor suppressor for renal cell carcinoma (1352 aa)
       0.869
RHOQ
ras homolog gene family, member Q; Plasma membrane-associated small GTPase which cycles between [...] (205 aa)
      0.808
DMRT1
doublesex and mab-3 related transcription factor 1; May be required for testis development (373 aa)
       0.778
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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