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  MAPK3 protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MAPK3
Mitogen-activated protein kinase 3 (EC 2.7.11.24) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase 1) (MAPK 1) (p44-ERK1) (ERT2) (p44-MAPK) (Microtubule- associated protein 2 kinase); Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates hea [...] (379 aa)
(Homo sapiens)
Predicted Functional Partners:
ELK1
ETS domain-containing protein Elk-1; Stimulates transcription. Binds to purine-rich DNA sequenc [...] (508 aa)
     0.999
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) [...] (393 aa)
    0.999
PTPN7
Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC [...] (465 aa)
     0.999
STAT3
Signal transducer and activator of transcription 3 (Acute-phase response factor); Transcription [...] (773 aa)
     0.999
DUSP6
Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein k [...] (381 aa)
     0.999
DUSP1
Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) ( [...] (367 aa)
     0.999
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.12.2) (MAP kinase kinase 2) [...] (400 aa)
    0.999
PTPN11
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2 [...] (593 aa)
     0.998
PTPRR
Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphat [...] (669 aa)
     0.998
NGFB
Beta-nerve growth factor precursor (Beta-NGF); Nerve growth factor is important for the develop [...] (241 aa)
      0.996
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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