STRINGSTRING
Dedd2 Dedd2 Prr19 Prr19 Cmss1 Cmss1 Maco1 Maco1 Zfp526 Zfp526 Tma16 Tma16 Ccdc73 Ccdc73 Zbtb11 Zbtb11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Dedd2DNA-binding death effector domain-containing protein 2; May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. (330 aa)    
Predicted Functional Partners:
Prr19
Proline-rich 19.
      
 0.548
Cmss1
Protein CMSS1; Belongs to the CMS1 family.
      
 0.534
Maco1
Macoilin; Plays a role in the regulation of neuronal activity. Belongs to the macoilin family.
   
  
 0.500
Zfp526
Zinc finger protein 526; May be involved in transcriptional regulation.
   
  
 0.463
Tma16
Translation machinery-associated protein 16.
      
 0.448
Ccdc73
Coiled-coil domain-containing protein 73.
      
 0.420
Zbtb11
Zinc finger and BTB domain-containing protein 11; May be involved in transcriptional regulation.
   
  
 0.401
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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