Frizzled-4 precursor (Fz-4) (hFz4) (FzE4) (CD344 antigen); Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inact [...] (537 aa)

Norrin precursor (Norrie disease protein); Activates the canonical Wnt signaling pathway throug [...] (133 aa)

Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2); May play a [...] (736 aa)

Low-density lipoprotein receptor-related protein 5 precursor; Involved in the Wnt/beta catenin [...] (1617 aa)

Protein Wnt-5a precursor; Ligand for members of the frizzled family of seven transmembrane rece [...] (380 aa)

Protein Wnt-3a precursor; Ligand for members of the frizzled family of seven transmembrane rece [...] (385 aa)

membrane-associated guanylate kinase-related 3 isoform 1; Acts as a scaffolding protein at cell [...] (1481 aa)

Low-density lipoprotein receptor-related protein 6 precursor; Essential for the Wnt/beta cateni [...] (1613 aa)

Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1); May play a [...] (695 aa)

Protein Wnt-2b precursor (Wnt-13); Ligand for members of the frizzled family of seven transmemb [...] (391 aa)

Protein Wnt-11 precursor; Ligand for members of the frizzled family of seven transmembrane rece [...] (354 aa)