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sen2 sen2 sen54 sen54 sen34 sen34 sen15 sen15 rpp40 rpp40 cwf5 cwf5 pop23 pop23 grc3 grc3 las1 las1 dhp1 dhp1 pop100 pop100
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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sen2Probable tRNA-splicing endonuclease subunit sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant s [...] (380 aa)    
Predicted Functional Partners:
sen54
Probable tRNA-splicing endonuclease subunit sen54; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of th [...]
   
 
 0.868
sen34
Probable tRNA-splicing endonuclease subunit sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant [...]
     
 0.865
sen15
Probable tRNA-splicing endonuclease subunit sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of th [...]
   
 
 0.770
rpp40
Uncharacterized protein C6C3.09.
    
 0.761
cwf5
Pre-mRNA-splicing factor cwf5; Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity). Involved in pre-mRNA splicing; Belongs to the RRM SLT11 family.
   
 
 0.754
pop23
Ribonucleases P/MRP protein subunit pop3; Required for processing of 5.8S rRNA (short form) at site A3 and for 5'- and 3'-processing of pre-tRNA.
   
  0.736
grc3
Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase required for both rRNA processing and heterochromatic gene silencing.
    
 0.735
las1
Pre-rRNA-processing protein las1; Required for both pre-rRNA processing and heterochromatic gene silencing.
   
  0.734
dhp1
5'-3' exoribonuclease 2; Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II (By similarity). Essential for vegetative cell growth and chromosome segregation. Possesses 5'->3' exoribonuclease activity.
    
  0.730
pop100
Ribonucleases P/MRP protein subunit pop1; Required for processing of 5.8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA; Belongs to the POP1 family.
    
  0.730
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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