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  Nfkbib protein (Mus musculus) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Nfkbib
nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation (359 aa)
(Mus musculus)
Predicted Functional Partners:
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian); NF-kappa-B is a pleiotropic trans [...] (549 aa)
     0.999
Ikbkb
inhibitor of kappaB kinase beta; Acts as part of the IKK complex in the conventional pathway of [...] (757 aa)
     0.997
Rel
reticuloendotheliosis oncogene; Proto-oncogene that may play a role in differentiation and lymp [...] (588 aa)
     0.997
Chuk
conserved helix-loop-helix ubiquitous kinase; Acts as part of the IKK complex in the convention [...] (745 aa)
     0.997
Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B; NF-kappa-B is a pleiotropic trans [...] (558 aa)
     0.995
Ikbkg
inhibitor of kappaB kinase gamma; Regulatory subunit of the IKK core complex which phosphorylat [...] (430 aa)
      0.989
Gorasp1
golgi reassembly stacking protein 1; Stacking factor involved in the postmitotic assembly of Go [...] (446 aa)
       0.949
Nfkb1
nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; NF-kappa-B is a pleiotrop [...] (971 aa)
    0.946
Tnf
tumor necrosis factor; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly s [...] (235 aa)
       0.942
Pmpcb
peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitocho [...] (489 aa)
       0.940
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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