node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4930438A08Rik | Cs | ENSMUSP00000104462 | ENSMUSP00000005826 | Amine oxidase. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.808 |
4930438A08Rik | Csl | ENSMUSP00000104462 | ENSMUSP00000052373 | Amine oxidase. | Citrate synthase; Belongs to the citrate synthase family. | 0.808 |
4930438A08Rik | Ddo | ENSMUSP00000104462 | ENSMUSP00000019977 | Amine oxidase. | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | 0.911 |
4930438A08Rik | Got1 | ENSMUSP00000104462 | ENSMUSP00000026196 | Amine oxidase. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.902 |
4930438A08Rik | Got1l1 | ENSMUSP00000104462 | ENSMUSP00000041337 | Amine oxidase. | Putative aspartate aminotransferase, cytoplasmic 2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.902 |
4930438A08Rik | Got2 | ENSMUSP00000104462 | ENSMUSP00000034097 | Amine oxidase. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. | 0.904 |
4930438A08Rik | Il4i1 | ENSMUSP00000104462 | ENSMUSP00000113726 | Amine oxidase. | L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation; Belongs to the flavin monoamine oxidase family. FIG1 subfamily. | 0.906 |
4930438A08Rik | Lao1 | ENSMUSP00000104462 | ENSMUSP00000062834 | Amine oxidase. | Amine oxidase. | 0.903 |
4930438A08Rik | Nit2 | ENSMUSP00000104462 | ENSMUSP00000023432 | Amine oxidase. | Omega-amidase NIT2; Possesses omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively. Can hydrolyze glutaramate, succinate and gamma- monomethyl-alpha-ketoglutarate in vitro. | 0.905 |
4930438A08Rik | Pcx | ENSMUSP00000104462 | ENSMUSP00000063825 | Amine oxidase. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.808 |
Cs | 4930438A08Rik | ENSMUSP00000005826 | ENSMUSP00000104462 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Amine oxidase. | 0.808 |
Cs | Csl | ENSMUSP00000005826 | ENSMUSP00000052373 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.906 |
Cs | Ddo | ENSMUSP00000005826 | ENSMUSP00000019977 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | 0.851 |
Cs | Got1 | ENSMUSP00000005826 | ENSMUSP00000026196 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.901 |
Cs | Got1l1 | ENSMUSP00000005826 | ENSMUSP00000041337 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Putative aspartate aminotransferase, cytoplasmic 2; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.891 |
Cs | Got2 | ENSMUSP00000005826 | ENSMUSP00000034097 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. | 0.948 |
Cs | Il4i1 | ENSMUSP00000005826 | ENSMUSP00000113726 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation; Belongs to the flavin monoamine oxidase family. FIG1 subfamily. | 0.808 |
Cs | Lao1 | ENSMUSP00000005826 | ENSMUSP00000062834 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Amine oxidase. | 0.816 |
Cs | Nit2 | ENSMUSP00000005826 | ENSMUSP00000023432 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Omega-amidase NIT2; Possesses omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively. Can hydrolyze glutaramate, succinate and gamma- monomethyl-alpha-ketoglutarate in vitro. | 0.810 |
Cs | Pcx | ENSMUSP00000005826 | ENSMUSP00000063825 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. | 0.984 |