Sfrp4 protein (Rattus norvegicus) - STRING interaction network

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	Sfrp4	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled- related protein) (FRP) (DDC-4 protein); Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity) (348 aa)
		(Rattus norvegicus)
Predicted Functional Partners:
	Wnt2	Wingless-type MMTV integration site family member 2; Ligand for members of the frizzled family [...] (360 aa)		•	•		0.946
	Wnt7a	WNT7A-like protein (Fragment); Ligand for members of the frizzled family of seven transmembrane [...] (349 aa)		•	•		0.899
	Sfrp2	Putative secreted frizzled related protein (Fragment) (295 aa)		•	•	•	0.842
	Sfrp1	Secreted frizzled-related protein 1 (sFRP-1) (Fragment); Soluble frizzled-related proteins (sFR [...] (313 aa)		•	•	•	0.837
	Fzd6	FZ6-like protein (Fragment) (710 aa)		•	•	•	0.831
	Fzd2	Frizzled-2 precursor (Fz-2) (rFz2); Receptor for Wnt proteins. Most of frizzled receptors are c [...] (570 aa)	•	•	•	•	0.829
	Fzd4	Frizzled-4 precursor (Fz-4) (rFz4) (CD344 antigen); Receptor for Wnt proteins. Most of frizzled [...] (538 aa)	•	•	•	•	0.827
	Fzd9	frizzled 9 (592 aa)		•	•	•	0.826
	Fz8	Frizzled-8 precursor (Fz-8); Receptor for Wnt proteins. Most of frizzled receptors are coupled [...] (684 aa)		•	•	•	0.825
	Fzd1	Frizzled-1 precursor (Fz-1) (rFz1); Receptor for Wnt proteins. Most of frizzled receptors are c [...] (642 aa)	•	•	•	•	0.823

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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