STRINGSTRING
kars-1 kars-1 mars-1 mars-1 qars-1 qars-1 rars-1 rars-1 lars-1 lars-1 iars-1 iars-1 pars-1 pars-1 ears-1 ears-1 gars-1 gars-1 eef-1G eef-1G hars-1 hars-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
kars-1Lysine--tRNA ligase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA; Belongs to the class-II aminoacyl-tRNA synthetase family. (596 aa)    
Predicted Functional Partners:
mars-1
Methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.999
qars-1
Probable glutamine--tRNA ligase.
  
 0.999
rars-1
Probable arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.
  
 
 0.998
lars-1
Leucine--tRNA ligase; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
  
 
 0.998
iars-1
Isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.995
pars-1
Prolyl Amino-acyl tRNA Synthetase.
  
 0.995
ears-1
Glutamyl(E) Amino-acyl tRNA Synthetase.
  
 0.989
gars-1
Glycine--tRNA ligase; Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis. Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.987
eef-1G
Probable elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 
 0.982
hars-1
Histidine--tRNA ligase; Involved in protein synthesis. Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (Probable). Required for germ cell development. Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.982
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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