STRING 9.1 
  VPS35 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae); Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA) (796 aa)
(Homo sapiens)
Predicted Functional Partners:
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae); Essential component of the retromer comple [...] (182 aa)
     0.999
VPS26B
vacuolar protein sorting 26 homolog B (S. pombe); Probable component of the retromer complex, a [...] (336 aa)
     0.993
VPS26A
vacuolar protein sorting 26 homolog A (S. pombe); Essential component of the retromer complex, [...] (327 aa)
     0.971
SNX1
sorting nexin 1; May be involved in several stages of intracellular trafficking. Plays a role i [...] (522 aa)
     0.917
PLIN3
perilipin 3; Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes t [...] (434 aa)
       0.859
GOLPH3
golgi phosphoprotein 3 (coat-protein); Involved in modulation of mTOR signaling. Involved in th [...] (298 aa)
      0.854
IGF2R
insulin-like growth factor 2 receptor; Transport of phosphorylated lysosomal enzymes from the G [...] (2491 aa)
     0.844
ANXA7
annexin A7; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved [...] (488 aa)
       0.792
UBC
ubiquitin C (685 aa)
      0.767
SNX8
sorting nexin 8; May be involved in several stages of intracellular trafficking (By similarity) (465 aa)
      0.728
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (16%)
Permalink