MDFI protein (Homo sapiens) - STRING network view

STRING 9.05

MDFI protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	MDFI	MyoD family inhibitor; Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the le [...] (246 aa)
		(Homo sapiens)
Predicted Functional Partners:
	AXIN1	axin 1; Controls dorsoventral patterning via two opposing effects; down-regulates beta-catenin [...] (862 aa)		•	0.829
	MYOD1	myogenic differentiation 1; Involved in muscle differentiation (myogenic factor). Induces fibro [...] (320 aa)	•	•	0.826
	MYOG	myogenin (myogenic factor 4); Involved in muscle differentiation (myogenic factor). Induces fib [...] (224 aa)	•	•	0.710
	FAM124B	family with sequence similarity 124B (455 aa)	•		0.703
	C10orf62	Uncharacterized protein C10orf62 (223 aa)	•		0.703
	CO	aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membr [...] (269 aa)	•		0.703
	MYF5	myogenic factor 5; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to [...] (255 aa)	•	•	0.701
	NEU4	sialidase 4; May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase [...] (496 aa)	•		0.671
	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; Involve [...] (287 aa)	•		0.671
	TRPC1	transient receptor potential cation channel, subfamily C, member 1; Thought to form a receptor- [...] (759 aa)	•	•	0.637

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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