UGT2B7 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	UGT2B7	UDP-glucuronosyltransferase 2B7 precursor (EC 2.4.1.17) (UDPGT) (3,4- catechol estrogen specific) (UDPGTh-2); UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (529 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CYP3A4	Cytochrome P450 3A4 (EC 1.14.13.67) (Quinine 3-monooxygenase) (CYPIIIA4) (Nifedipine oxidase) ( [...] (503 aa)	•		•	0.977
	SLC35A2	UDP-galactose translocator (UDP-galactose transporter) (UGT) (UDP-Gal- Tr) (Solute carrier fami [...] (396 aa)			•	0.957
	CYP2E1	Cytochrome P450 2E1 (EC 1.14.14.1) (CYPIIE1) (P450-J); Metabolizes several precarcinogens, drug [...] (493 aa)		•	•	0.947
	CYP2B6	Cytochrome P450 2B6 (EC 1.14.14.1) (CYPIIB6) (P450 IIB1); Cytochromes P450 are a group of heme- [...] (491 aa)		•	•	0.942
	CDX2	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3); Involved in the transciptional [...] (313 aa)			•	0.926
	GUSB	Beta-glucuronidase precursor (EC 3.2.1.31) (Beta-G1); Plays an important role in the degradatio [...] (651 aa)		•	•	0.923
	UGDH	UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH); Involve [...] (494 aa)		•	•	0.922
	SULT1E1	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1); May co [...] (294 aa)		•	•	0.916
	ADHFE1	alcohol dehydrogenase, iron containing, 1; Catalyzes the cofactor-independent reversible oxidat [...] (419 aa)		•	•	0.909
	METTL6	Methyltransferase-like protein 6 (EC 2.1.1.-); Probable methyltransferase (By similarity) (255 aa)		•		0.899

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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