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nagA nagA murQ murQ FTT_0599 FTT_0599 glmS glmS mrsA mrsA yeaZ yeaZ aspC2 aspC2 FTT_1166c FTT_1166c rbfA rbfA ylqF ylqF FTT_0928c FTT_0928c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nagASimilar to Q99VS2 NagA protein (Probable N-acetylglucosamine-6-phosphate deacetylase) from Staphylococcus aureus (393 aa). FASTA: opt: 1006 Z-score: 1213.0 E(): 1.1e-59 Smith-Waterman score: 1006; 43.523 identity in 386 aa overlap. (377 aa)    
Predicted Functional Partners:
murQ
Glucokinase regulatory protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
  
 0.986
FTT_0599
Similar to Q9AAR1 SIS domain protein from Caulobacter crescentus (358 aa). FASTA: opt: 864 Z-score: 1052.1 E(): 1e-50 Smith-Waterman score: 864; 42.353 identity in 340 aa overlap. Putative Glucosamine-fructose-6-phosphate aminotransferase ORF ftt0599.
 
 
 0.946
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.932
mrsA
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
  
 0.919
yeaZ
Glycoprotease family protein; Similar to Q8EE04 (Q8EE04) Conserved hypothetical protein from Shewanella oneidensis (236 aa). FASTA: opt: 349 Z-score: 425.3 E(): 8.5e-16 Smith-Waterman score: 359; 32.273 identity in 220 aa overlap. ORF ftt1167c.
  
    0.797
aspC2
Similar to Q83E19 Aspartate aminotransferase from Coxiella burnetii (394 aa). FASTA: opt: 1067 Z-score: 1292.7 E(): 4.1e-64 Smith-Waterman score: 1067; 41.645 identity in 389 aa overlap.
  
    0.779
FTT_1166c
Glutamine amidotransferases class-II family protein; Similar to Q8D5X6 Predicted glutamine amidotransferase from Vibrio vulnificus (253 aa). FASTA: opt: 654 Z-score: 813.9 E(): 1.9e-37 Smith-Waterman score: 654; 42.466identity in 219 aa overlap. ORF ftt1166c.
       0.777
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
     
 0.762
ylqF
GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
    0.577
FTT_0928c
SImilar to Q8RD12 Beta-glucosidase-related glycosidases from Thermoanaerobacter tengcongensis (591 aa). FASTA: opt: 1047 Z-score: 1141.5 E(): 9.9e-56 Smith-Waterman score: 1062; 35.106 identity in 564 aa overlap. ORF ftt0928c.
 
  
 0.554
Your Current Organism:
Francisella tularensis SCHUS4
NCBI taxonomy Id: 177416
Other names: F. tularensis subsp. tularensis SCHU S4, Francisella tularensis Biovar A str. SCHU S4, Francisella tularensis Biovar A str. Schu 4, Francisella tularensis subsp. tularensis SCHU S4, Francisella tularensis subsp. tularensis Schu 4, Francisella tularensis subsp. tularensis str. SCHU S4, Francisella tularensis subsp. tularensis strain SCHU S4
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