PIK3CB protein (Homo sapiens) - STRING interaction network

PIK3CB protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta); Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2 (1070 aa)
		(Homo sapiens)
Predicted Functional Partners:
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3 [...] (724 aa)	•	•	•	0.997
	IRS1	Insulin receptor substrate 1 (IRS-1); May mediate the control of various cellular processes by [...] (1242 aa)		•	•	0.988
	PTEN	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatas [...] (403 aa)	•	•	•	0.986
	AKT1	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) [...] (480 aa)		•	•	0.984
	IRS2	Insulin receptor substrate 2 (IRS-2); May mediate the control of various cellular processes by [...] (1338 aa)		•	•	0.975
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3- [...] (728 aa)		•	•	0.971
	INS	Insulin precursor [Contains- Insulin B chain; Insulin A chain]; Insulin decreases blood glucose [...] (110 aa)		•	•	0.966
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3 [...] (461 aa)	•	•	•	0.963
	ARHGEF7	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (COO [...] (803 aa)			•	0.961
	IGF1	Insulin-like growth factor IA precursor (IGF-IA) (Somatomedin C) (Mechano growth factor) (MGF); [...] (195 aa)		•	•	0.955

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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