Vav3 protein (Mus musculus) - STRING interaction network

Vav3 protein (Mus musculus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	Vav3	vav 3 oncogene; Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases (By similarity) (847 aa)
		(Mus musculus)
Predicted Functional Partners:
	Lcp2	lymphocyte cytosolic protein 2; Involved in T-cell antigen receptor mediated signaling (533 aa)	•	•	•		0.983
	Rhoa	ras homolog gene family, member A; Regulates a signal transduction pathway linking plasma membr [...] (193 aa)		•	•		0.975
	Rac2	RAS-related C3 botulinum substrate 2; Plasma membrane-associated small GTPase which cycles betw [...] (192 aa)		•	•		0.964
	Cdc42	cell division cycle 42 homolog (S. cerevisiae); Plasma membrane-associated small GTPase which c [...] (191 aa)		•	•		0.964
	Rhog	ras homolog gene family, member G; Required for the formation of membrane ruffles during macrop [...] (191 aa)		•	•		0.960
	Syk	spleen tyrosine kinase; Positive effector of BCR-stimulated responses. Couples the B-cell antig [...] (629 aa)	•	•	•	•	0.947
	Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide; Associates with a variety of FcR alpha ch [...] (86 aa)		•	•		0.926
	Zap70	zeta-chain (TCR) associated protein kinase; Plays a role in T-cell development and lymphocyte a [...] (618 aa)		•	•	•	0.915
	Grb2	growth factor receptor bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)	•	•	•	•	0.914
	Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog (491 aa)		•	•	•	0.914

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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