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IGSF9 IGSF9 IGSF21 IGSF21 FN1 FN1 NTS NTS VSIG2 VSIG2 PRR15 PRR15 BICDL1 BICDL1 NMRK1 NMRK1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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IGSF9Protein turtle homolog A; Functions in dendrite outgrowth and synapse maturation. Belongs to the immunoglobulin superfamily. Turtle family. (1179 aa)    
Predicted Functional Partners:
IGSF21
Immunoglobulin superfamily member 21; Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.
   
 
 0.601
FN1
Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
    
 
 0.482
NTS
Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle; Belongs to the neurotensin family.
   
  
 0.470
VSIG2
V-set and immunoglobulin domain containing 2.
   
  
 0.454
PRR15
Proline-rich protein 15; May have a role in proliferation and/or differentiation.
   
  
 0.432
BICDL1
BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6- containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity). Belongs to the BICDR family.
    
 
 0.403
NMRK1
Nicotinamide riboside kinase 1; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine. Belongs to the uridine kinase family. NRK subfamily.
    
 
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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