node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | AMBP | ENSSSCP00000053712 | ENSSSCP00000029018 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | 0.799 |
ALB | CYP1A1 | ENSSSCP00000053712 | ENSSSCP00000002085 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.586 |
ALB | FAH | ENSSSCP00000053712 | ENSSSCP00000064003 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Fumarylacetoacetase. | 0.612 |
ALB | SERPINA7 | ENSSSCP00000053712 | ENSSSCP00000013341 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.632 |
ALB | TTR | ENSSSCP00000053712 | ENSSSCP00000072347 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family. | 0.842 |
AMBP | ALB | ENSSSCP00000029018 | ENSSSCP00000053712 | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.799 |
AMBP | SERPINA7 | ENSSSCP00000029018 | ENSSSCP00000013341 | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.605 |
AMBP | TTR | ENSSSCP00000029018 | ENSSSCP00000072347 | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family. | 0.715 |
BPIFB4 | SERPINA7 | ENSSSCP00000045292 | ENSSSCP00000013341 | BPI fold containing family B member 4. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.545 |
CYP1A1 | ALB | ENSSSCP00000002085 | ENSSSCP00000053712 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.586 |
CYP1A1 | SERPINA7 | ENSSSCP00000002085 | ENSSSCP00000013341 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.828 |
F9 | SERPINA7 | ENSSSCP00000013514 | ENSSSCP00000013341 | Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.750 |
FAH | ALB | ENSSSCP00000064003 | ENSSSCP00000053712 | Fumarylacetoacetase. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.612 |
FAH | SERPINA7 | ENSSSCP00000064003 | ENSSSCP00000013341 | Fumarylacetoacetase. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.607 |
FAH | TTR | ENSSSCP00000064003 | ENSSSCP00000072347 | Fumarylacetoacetase. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Belongs to the transthyretin family. | 0.467 |
IRS4 | SERPINA7 | ENSSSCP00000028502 | ENSSSCP00000013341 | Insulin receptor substrate 4. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.560 |
LECT2 | SERPINA7 | ENSSSCP00000015226 | ENSSSCP00000013341 | Leukocyte cell derived chemotaxin 2. | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | 0.936 |
LECT2 | SLCO1B3 | ENSSSCP00000015226 | ENSSSCP00000025888 | Leukocyte cell derived chemotaxin 2. | Solute carrier organic anion transporter family member. | 0.938 |
SERPINA7 | ALB | ENSSSCP00000013341 | ENSSSCP00000053712 | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.632 |
SERPINA7 | AMBP | ENSSSCP00000013341 | ENSSSCP00000029018 | Thyroxine-binding globulin; Major thyroid hormone transport protein in serum. Belongs to the serpin family. | Inter-alpha-trypsin inhibitor light chain; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization; In the N-terminal section; belongs to the calycin superfamily. Lipocalin family. | 0.605 |