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  CD8B protein (Homo sapiens) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CD8B
T-cell surface glycoprotein CD8 beta chain precursor (CD8b antigen); Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (246 aa)
(Homo sapiens)
Predicted Functional Partners:
CD8A
T-cell surface glycoprotein CD8 alpha chain precursor (T-lymphocyte differentiation antigen T8/ [...] (235 aa)
    ••• 0.999
CD4
T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3); Accessory protein [...] (458 aa)
     •• 0.978
IL2RA
Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) ( [...] (272 aa)
     •• 0.977
IL2
Interleukin-2 precursor (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin); Produced by T-cells [...] (153 aa)
     •• 0.976
CD3D
T-cell surface glycoprotein CD3 delta chain precursor (T-cell receptor T3 delta chain); The CD3 [...] (171 aa)
    ••• 0.969
LCK
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific pr [...] (539 aa)
     •• 0.959
B2M
Beta-2-microglobulin precursor [Contains- Beta-2-microglobulin variant pI 5.3]; Beta-2-microglo [...] (119 aa)
     •• 0.949
IL2RB
Interleukin-2 receptor subunit beta precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL- [...] (551 aa)
     •• 0.947
CD247
T-cell surface glycoprotein CD3 zeta chain precursor (T-cell receptor T3 zeta chain) (CD247 ant [...] (261 aa)
     •• 0.937
CD3E
T-cell surface glycoprotein CD3 epsilon chain precursor (T-cell surface antigen T3/Leu-4 epsilo [...] (207 aa)
     •• 0.930
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth
       
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