SOS1 protein (Homo sapiens) - STRING network view

STRING 9.05

SOS1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	SOS1	son of sevenless homolog 1 (Drosophila); Promotes the exchange of Ras-bound GDP by GTP (1333 aa)
		(Homo sapiens)
Predicted Functional Partners:
	GRB2	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)	•	•	•	0.999
	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intri [...] (189 aa)	•	•	•	0.999
	SHC1	SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)	•	•	•	0.999
	EPS8	epidermal growth factor receptor pathway substrate 8; Upon binding to EGF receptor enhances EGF [...] (822 aa)	•	•	•	0.999
	EGFR	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)	•	•	•	0.998
	NCK1	NCK adaptor protein 1; Adapter protein which associates with tyrosine- phosphorylated growth fa [...] (377 aa)	•	•		0.997
	PLCG1	phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)	•	•	•	0.996
	FRS2	fibroblast growth factor receptor substrate 2; Adapter protein that links FGR and NGF receptors [...] (508 aa)	•	•	•	0.995
	PTPN11	protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cyt [...] (593 aa)	•	•	•	0.992
	ABI1	abl-interactor 1; May act in negative regulation of cell growth and transformation by interacti [...] (508 aa)	•	•	•	0.992

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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