STRINGSTRING
spo3 spo3 npg1 npg1 spo14 spo14 spo15 spo15 spo2 spo2 psy1 psy1 meu14 meu14 spo6 spo6 spo13 spo13 spo20 spo20 spo4 spo4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
spo3Sporulation-specific protein 3; Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane. (1028 aa)    
Predicted Functional Partners:
npg1
Uncharacterized protein C17D1.07c.
   
 
 0.896
spo14
Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1.
      
 0.871
spo15
Sporulation-specific protein 15; Has a role in the initiation of spore membrane formation.
      
 0.827
spo2
Sporulation-specific protein 2; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation. Assists in the localization of spo13 to the outer surface of the SPB.
      
 0.826
psy1
Syntaxin-like protein psy1.
    
 
 0.806
meu14
Meiotic expression up-regulated protein 14; Has a role in nuclear division during meiosis II where it stabilizes the proper segregation of the spindle pole bodies. Also has a role in the formation and extension of the forespore membrane.
   
  
 0.768
spo6
Sporulation-specific protein 6; May act as a kinase regulator. Essential for progression of meiosis II and sporulation.
   
  
 0.761
spo13
Sporulation-specific protein 13; Involved in sporulation. Plays a significant role in modification of the spindle pole body prior to spore formation and is required for initiating forespore membrane formation.
      
 0.759
spo20
Sec14 cytosolic factor; Required for transport of secretory proteins from the Golgi complex. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro. Essential for viability and secretion.
      
 0.750
spo4
Cell cycle protein kinase spo4; Required for the initiation of meiosis II and progression through anaphase II.
   
  
 0.749
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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