node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPAC3H1.08c | aca1 | Q10073 | Q09927 | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...] | 0.575 |
SPAC3H1.08c | clg1 | Q10073 | O14336 | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | Meiotically up-regulated gene 80 protein; Has a role in meiosis. | 0.457 |
SPAC3H1.08c | mpr1 | Q10073 | O94321 | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | Multistep phosphorelay regulator 1; Binds to the msc4 response regulator which is part of a multistep phosphorelay system that transmits oxidative stress signals to the spc1 MAPK cascade. | 0.491 |
SPAC3H1.08c | pef1 | Q10073 | O74456 | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | Serine/threonine-protein kinase pef1. | 0.498 |
SPAC3H1.08c | pex8 | Q10073 | Q9UT96 | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | Uncharacterized protein C323.03c. | 0.630 |
aca1 | SPAC3H1.08c | Q09927 | Q10073 | N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...] | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | 0.575 |
aca1 | mpr1 | Q09927 | O94321 | N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...] | Multistep phosphorelay regulator 1; Binds to the msc4 response regulator which is part of a multistep phosphorelay system that transmits oxidative stress signals to the spc1 MAPK cascade. | 0.777 |
aca1 | pef1 | Q09927 | O74456 | N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...] | Serine/threonine-protein kinase pef1. | 0.409 |
aca1 | pex8 | Q09927 | Q9UT96 | N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...] | Uncharacterized protein C323.03c. | 0.498 |
clg1 | SPAC3H1.08c | O14336 | Q10073 | Meiotically up-regulated gene 80 protein; Has a role in meiosis. | Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial. | 0.457 |
clg1 | pef1 | O14336 | O74456 | Meiotically up-regulated gene 80 protein; Has a role in meiosis. | Serine/threonine-protein kinase pef1. | 0.904 |
clg1 | pex8 | O14336 | Q9UT96 | Meiotically up-regulated gene 80 protein; Has a role in meiosis. | Uncharacterized protein C323.03c. | 0.420 |
csc4 | ebs1 | O14043 | O14338 | Uncharacterized protein C2C4.10c. | Uncharacterized serine-rich protein C2F12.03c. | 0.623 |
csc4 | far10 | O14043 | O74388 | Uncharacterized protein C2C4.10c. | Uncharacterized protein C3H7.13. | 0.990 |
csc4 | far8 | O14043 | O94560 | Uncharacterized protein C2C4.10c. | Uncharacterized WD repeat-containing protein C1773.01. | 0.982 |
csc4 | lam2 | O14043 | Q9Y7J2 | Uncharacterized protein C2C4.10c. | Uncharacterized protein C1778.05c. | 0.532 |
csc4 | pex8 | O14043 | Q9UT96 | Uncharacterized protein C2C4.10c. | Uncharacterized protein C323.03c. | 0.723 |
ebs1 | csc4 | O14338 | O14043 | Uncharacterized serine-rich protein C2F12.03c. | Uncharacterized protein C2C4.10c. | 0.623 |
ebs1 | far10 | O14338 | O74388 | Uncharacterized serine-rich protein C2F12.03c. | Uncharacterized protein C3H7.13. | 0.426 |
ebs1 | far8 | O14338 | O94560 | Uncharacterized serine-rich protein C2F12.03c. | Uncharacterized WD repeat-containing protein C1773.01. | 0.422 |