STRINGSTRING
pex8 pex8 csc4 csc4 SPAC3H1.08c SPAC3H1.08c aca1 aca1 far10 far10 ebs1 ebs1 pef1 pef1 far8 far8 lam2 lam2 mpr1 mpr1 clg1 clg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
pex8Uncharacterized protein C323.03c. (575 aa)    
Predicted Functional Partners:
csc4
Uncharacterized protein C2C4.10c.
      
 0.723
SPAC3H1.08c
Uncharacterized CCDC90 family protein C3H1.08c, mitochondrial.
      
 0.630
aca1
N-acetyltransferase aca1; N-acetyltransferase involved in oxidative stress resistance. Acetylates the toxic proline metabolism intermediate (S)-1-pyrroline-5- carboxylate (P5C), or more likely its spontaneously forming tautomer glutamate-5-semialdehyde (GSA) into N-acetyl-GSA for arginine synthesis in the mitochondria. P5C has been shown to increase the levels of reactive oxigen species (ROS) in the cell by inhibiting the function of the respiratory chain in the mitochondria. The enzyme is able to reduce intracellular ROS levels under P5C-induced oxidative stress and protects cells fro [...]
   
  
 0.498
far10
Uncharacterized protein C3H7.13.
   
  
 0.496
ebs1
Uncharacterized serine-rich protein C2F12.03c.
      
 0.495
pef1
Serine/threonine-protein kinase pef1.
    
 
 0.464
far8
Uncharacterized WD repeat-containing protein C1773.01.
      
 0.459
lam2
Uncharacterized protein C1778.05c.
   
  
 0.452
mpr1
Multistep phosphorelay regulator 1; Binds to the msc4 response regulator which is part of a multistep phosphorelay system that transmits oxidative stress signals to the spc1 MAPK cascade.
      
 0.424
clg1
Meiotically up-regulated gene 80 protein; Has a role in meiosis.
      
 0.420
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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