STRING 10 
  ANGPT4 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ANGPT4
angiopoietin 4; Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis (503 aa)
(Homo sapiens)
Predicted Functional Partners:
TEK
TEK tyrosine kinase, endothelial; Tyrosine-protein kinase that acts as cell-surface receptor fo [...] (1124 aa)
     0.998
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1; Transmembrane tyrosine-protein [...] (1138 aa)
      0.986
ANGPT2
angiopoietin 2; Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 [...] (496 aa)
     0.904
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase); Tyrosine-protein kinase th [...] (1356 aa)
     0.876
FLT1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor [...] (1338 aa)
     0.872
FLT4
fms-related tyrosine kinase 4; Tyrosine-protein kinase that acts as a cell-surface receptor for [...] (1363 aa)
     0.857
AKT1
v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonin [...] (480 aa)
       0.835
PDGFRB
platelet-derived growth factor receptor, beta polypeptide; Tyrosine-protein kinase that acts as [...] (1106 aa)
     0.821
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; Tyrosine-protein kinase that act [...] (976 aa)
     0.809
EGFR
epidermal growth factor receptor (1210 aa)
      0.808
 
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Co-expression Experiments Databases Textmining
 
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