STRING 9.1 
  IKBKG protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa- B-mediated protection from cytokine toxicity (By similarity) (487 aa)
(Homo sapiens)
Predicted Functional Partners:
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; Acts as part of the [...] (756 aa)
    0.999
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Inhibits t [...] (317 aa)
     0.999
CHUK
conserved helix-loop-helix ubiquitous kinase; Acts as part of the IKK complex in the convention [...] (745 aa)
     0.999
RIPK1
receptor (TNFRSF)-interacting serine-threonine kinase 1; Involved in the transduction of TNF si [...] (671 aa)
     0.999
CYLD
cylindromatosis (turban tumor syndrome); Negative regulator of TRAF2 and NF-kappa-B signaling p [...] (956 aa)
     0.999
TRAF6
TNF receptor-associated factor 6; Adapter protein and signal transducer that links members of t [...] (522 aa)
    0.999
UBC
ubiquitin C (685 aa)
       0.999
BCL10
B-cell CLL/lymphoma 10; Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa [...] (233 aa)
     0.998
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1; Enhances BCL10-induced activat [...] (824 aa)
     0.998
BIRC2
baculoviral IAP repeat-containing 2; Apoptotic suppressor. The BIR motifs region interacts with [...] (618 aa)
     0.998
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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