IKBKG protein (Homo sapiens) - STRING network view

STRING 9.05

IKBKG protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa- B-mediated protection from cytokine toxicity (By similarity) (487 aa)
		(Homo sapiens)
Predicted Functional Partners:
	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; Acts as part of the [...] (756 aa)		•	•	•	•	0.999
	CHUK	conserved helix-loop-helix ubiquitous kinase; Acts as part of the IKK complex in the convention [...] (745 aa)		•	•	•		0.999
	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Inhibits t [...] (317 aa)		•	•	•		0.999
	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1; Involved in the transduction of TNF si [...] (671 aa)		•	•	•		0.999
	CYLD	cylindromatosis (turban tumor syndrome); Negative regulator of TRAF2 and NF-kappa-B signaling p [...] (956 aa)		•	•	•		0.999
	TRAF6	TNF receptor-associated factor 6; Adapter protein and signal transducer that links members of t [...] (522 aa)	•	•	•	•		0.999
	UBC	ubiquitin C (685 aa)		•				0.999
	BCL10	B-cell CLL/lymphoma 10; Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa [...] (233 aa)		•	•	•		0.998
	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1; Enhances BCL10-induced activat [...] (824 aa)		•	•	•		0.998
	BIRC2	baculoviral IAP repeat-containing 2; Apoptotic suppressor. The BIR motifs region interacts with [...] (618 aa)		•	•	•		0.998

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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