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  Ctla4 protein (Mus musculus) - STRING interaction network
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Ctla4
cytotoxic T-lymphocyte-associated protein 4; Possibly involved in T-cell activation. Binds to B7-1 (CD80) and B7-2 (CD86) (223 aa)
(Mus musculus)
Predicted Functional Partners:
Cd86
CD86 antigen; Receptor involved in the costimulatory signal essential for T-lymphocyte prolifer [...] (356 aa)
    ••• 0.999
ENSMUSG00000075122
CD80 antigen; Involved in the costimulatory signal essential for T lymphocytes activation. T-ce [...] (306 aa)
    ••• 0.999
Ptpn11
protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cyt [...] (597 aa)
    ••• 0.992
Il2
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (169 aa)
      • 0.991
Il10
interleukin 10; Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL- [...] (178 aa)
      • 0.990
Lyn
Yamaguchi sarcoma viral (v-yes-1) oncogene homolog (491 aa)
    ••• 0.974
Fyn
Fyn proto-oncogene; Implicated in the control of cell growth. Plays a role in the regulation of [...] (537 aa)
    ••• 0.974
Icos
inducible T-cell co-stimulator; Enhances all basic T-cell responses to a foreign antigen, namel [...] (223 aa)
      • 0.961
Cd4
CD4 antigen; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regula [...] (457 aa)
      • 0.961
Foxp3
forkhead box P3; Probable transcription factor. Plays a critical role in the control of immune [...] (429 aa)
     •• 0.950
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes         or: network depth
       
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