Acly protein (Rattus norvegicus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	Acly	ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme); ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
		(Rattus norvegicus)
Predicted Functional Partners:
	Aco2	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) (780 aa)	•	•	0.928
	Mdh2	Malate dehydrogenase, mitochondrial precursor (EC 1.1.1.37) (338 aa)	•	•	0.927
	Pc	Pyruvate carboxylase, mitochondrial precursor (EC 6.4.1.1) (Pyruvic carboxylase) (PCB); Pyruvat [...] (1178 aa)	•	•	0.922
	Aco1	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferrit [...] (897 aa)	•	•	0.904
	Pck1	Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (EC 4.1.1.32) (Phosphoenolpyruvate carboxyla [...] (622 aa)	•		0.899
	Pck2	Pck2 protein (666 aa)	•		0.899
	Mdh1	Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (333 aa)	•		0.899
	CS	Citrate synthase, mitochondrial precursor (EC 2.3.3.1) (466 aa)	•	•	0.874
	Acaca	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes- Biotin carboxylase (EC 6.3.4.14)]; [...] (2347 aa)	•	•	0.850
	Acacb	acetyl-Coenzyme A carboxylase beta (2455 aa)	•	•	0.847

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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