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Klf6 | Krueppel-like factor 6; Transcriptional activator. Binds a GC box motif. Could play a role in B-cell growth and development (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. (318 aa) | ||||
Frs2 | Fibroblast growth factor receptor substrate 2; Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. (508 aa) |