Your Input: | |||||
Ncoa2 | Nuclear receptor coactivator 2; Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by [...] (1462 aa) | ||||
Akr1b7 | Aldo-keto reductase family 1 member B7; Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. Reduces prostaglandins. May play a role in the metabolism of xenobiotic aromatic aldehydes (By similarity); Belongs to the aldo/keto reductase family. (316 aa) |