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The following proteins in
Mus musculus
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '10090.ENSMUSP00000015841':
Setdb1 - Histone-lysine N-methyltransferase SETDB1; Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys- 9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' [...]
[a.k.a. ENSMUST00000152260.1, ENSMUSP00000015841, Histone-lysine N-methyltransferase SETDB1]
2) 'A730008H23Rik':
Hjurp - Holliday junction recognition protein; Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
[a.k.a.
A730008H23Rik
, ENSMUST00000147393.1, NM_172505.4]