Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
The following proteins in
Mus musculus
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '10090.ENSMUSP00000018287':
- - Sorry, STRING found no proteins by this name in Mus musculus - -
2) '10090.ENSMUSP00000046774':
Dennd3 - DENN domain-containing protein 3; Guanine nucleotide exchange factor (GEF) activating Rab12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab12 into its active GTP-bound form. Regulates autophagy in response to starvation through Rab12 activation. Starvation leads to ULK1/2-dependent phosphorylation of Ser-554 and Ser-572, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards Rab12. Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the degradation of the [...]
[a.k.a. ENSMUST00000160267.2, NP_001074535.1, NM_001081066.1]