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My Data
The following proteins in
Mus musculus
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '10090.ENSMUSP00000018681':
- - Sorry, STRING found no proteins by this name in Mus musculus - -
2) '10090.ENSMUSP00000131029':
Keap1 - Kelch-like ECH-associated protein 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine [...]
[a.k.a. R-MMU-1280218, Inrf2, NP_001103775.1]