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Cdx2 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. (311 aa) | ||||
Pigz | GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues (By similarity). (560 aa) |