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Mecp2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC). (501 aa) | ||||
Ifi27l2b | Interferon alpha-inducible protein 27-like protein 2B; Functions in the intrinsic apoptotic signaling pathway and may have an interferon-induced antiviral activity. Belongs to the IFI6/IFI27 family. (283 aa) |