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Nr0b2 | Nuclear receptor subfamily 0 group B member 2; Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with which it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1 (By similarity). Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2- mediated hepatic lipid metabolism. Regulates the [...] (260 aa) | ||||
Scrt1 | Transcriptional repressor scratch 1; Transcriptional repressor that binds E-box motif CAGGTG (By similarity). Appears to function downstream of proneural bHLH proteins in promoting neural differentiation. (348 aa) |