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Prdm14 | PR domain zinc finger protein 14; Transcription factor that has both positive and negative roles on transcription (By similarity). Plays a role in cellular pluripotency. Essential for germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (561 aa) | ||||
Rnd2 | Rho-related GTP-binding protein RhoN; May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity); Belongs to the small GTPase superfamily. Rho family. (227 aa) |