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Tle1 | Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG (By similarity); Belongs to the WD repeat Groucho/TLE family. (770 aa) | ||||
Igbp1b | Immunoglobulin-binding protein 1b; Associated to surface IgM-receptor; may be involved in signal transduction (By similarity). May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases. Belongs to the IGBP1/TAP42 family. (343 aa) |