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Dbp | D site-binding protein; This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation (By similarity). Belongs to the bZIP family. PAR subfamily. (325 aa) | ||||
Fam120a | Constitutive coactivator of PPAR-gamma-like protein 1; Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3- kinase. Binds RNA and promotes the secretion of IGF-II (By similarity). May participate in mRNA transport in the cytoplasm. (1112 aa) |