Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
The following proteins in
Mus musculus
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '10090.ENSMUSP00000084896':
- - Sorry, STRING found no proteins by this name in Mus musculus - -
2) '10090.ENSMUSP00000034349':
Nae1 - NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation (By similarity); Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
[a.k.a. ENSMUST00000159393, NEDD8-activating enzyme E1 regulatory subunit, R-MMU-392499]