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Pax6 | Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). (436 aa) | ||||
Ptpn21 | Tyrosine-protein phosphatase non-receptor type 21; May be involved in the regulation of growth and differentiation of liver cells; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1176 aa) |