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Pknox1 | Homeobox protein PKNOX1; Activates transcription in the presence of PBX1A and HOXA1. Belongs to the TALE/MEIS homeobox family. (436 aa) | ||||
Lmtk3 | Serine/threonine-protein kinase LMTK3; Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (By similarity). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. (1424 aa) |