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Asxl3 | Putative Polycomb group protein ASXL3; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). (2204 aa) | ||||
Ptpn21 | Tyrosine-protein phosphatase non-receptor type 21; May be involved in the regulation of growth and differentiation of liver cells; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1176 aa) |