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Klf4 | Krueppel-like factor 4; Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also fu [...] (483 aa) | ||||
Ly6g6e | Lymphocyte antigen 6G6e; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro potentiates alpha-3:beta-4- containing nAChRs maximum response by increasing peak current and slowing down receptor desensitization; the activity is dependent on its cell surface localization. (134 aa) |