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Ebf4 | Transcription factor COE4; Seems to weakly activate transcription. Binds an Olf-1 consensus site in vitro; Belongs to the COE family. (599 aa) | ||||
Eomes | Eomesodermin homolog; Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. (707 aa) |